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DHCR7


Official Full Name
7-dehydrocholesterol reductase
Organism
Homo sapiens
Gene ID
1717
Background
This gene encodes an enzyme that removes the C(7-8) double bond in the B ring of sterols and catalyzes the conversion of 7-dehydrocholesterol to cholesterol. This gene is ubiquitously expressed and its transmembrane protein localizes to the endoplasmic reticulum membrane and nuclear outer membrane. Mutations in this gene cause Smith-Lemli-Opitz syndrome (SLOS); a syndrome that is metabolically characterized by reduced serum cholesterol levels and elevated serum 7-dehydrocholesterol levels and phenotypically characterized by cognitive disability, facial dysmorphism, syndactyly of second and third toes, and holoprosencephaly in severe cases to minimal physical abnormalities and near-normal intelligence in mild cases. Alternative splicing results in multiple transcript variants that encode the same protein.[provided by RefSeq, Aug 2009]
Synonyms
SLOS

Cat.No. Product Name Price
SHH003395 shRNA set against Human DHCR7(NM_001360.2) Inquiry
SHH003413 shRNA set against Rat Dhcr7(NM_022389.2) Inquiry
SHH003431 shRNA set against Mouse Dhcr7(NM_007856.2) Inquiry
SHH277577 shRNA set against Human DHCR7 (NM_001360.2) Inquiry
SHH277581 shRNA set against Mouse DHCR7 (NM_007856.2) Inquiry
SHH277585 shRNA set against Rat DHCR7 (NM_022389.2) Inquiry
SHW003283 shRNA set against Chicken DHCR7 (NM_001199490) Inquiry
SHW017363 shRNA set against Danio rerio DHCR7 (NM_201330) Inquiry
Cat.No. Product Name Price
CDCR055258 Mouse Dhcr7 ORF clone (NM_007856.2) Inquiry
CDFH005034 Human DHCR7 cDNA Clone(NM_001163817.1) Inquiry
CDFR011838 Rat Dhcr7 cDNA Clone(NM_022389.2) Inquiry
MiUTR1H-02804 DHCR7 miRNA 3'UTR clone Inquiry
MiUTR1M-03834 DHCR7 miRNA 3'UTR clone Inquiry
MiUTR1R-01479 DHCR7 miRNA 3'UTR clone Inquiry
MiUTR3H-05358 DHCR7 miRNA 3'UTR clone Inquiry
CDCB164758 Chicken DHCR7 ORF Clone (NM_001199490) Inquiry
CDCB178838 Danio rerio DHCR7 ORF Clone (NM_201330) Inquiry
CDCR055256 Human DHCR7 ORF clone (NM_001163817.1) Inquiry
CDCR280615 Human DHCR7 ORF Clone(NM_001360.2) Inquiry
CDCR378997 Rat Dhcr7 ORF Clone(NM_022389.2) Inquiry
CDCS408733 Human DHCR7 ORF Clone (BC000054) Inquiry
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