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dfna5b

Official Full Name
gasdermin Eb
Organism
Danio rerio
GeneID
335722
Background
Acts upstream of or within with a positive effect on pyroptotic inflammatory response. Acts upstream of or within inner ear morphogenesis and regulation of biosynthetic process. Predicted to be located in endomembrane system and plasma membrane. Predicted to be active in cytoplasm. Is expressed in several structures, including hematopoietic system; liver; nervous system; pericardial region; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 5 and sensorineural hearing loss. Orthologous to human GSDME (gasdermin E). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
dfna5; dfna5b; fk59f08; zgc:91916; wu:fc41e05; wu:fk59f08;

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