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DEFA4


Official Full Name
defensin alpha 4
Organism
Homo sapiens
Gene ID
1669
Background
Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes are clustered on chromosome 8. This gene differs from other genes of this family by an extra 83-base segment that is apparently the result of a recent duplication within the coding region. The protein encoded by this gene, defensin, alpha 4, is found in the neutrophils; it exhibits corticostatic activity and inhibits corticotropin stimulated corticosterone production. [provided by RefSeq, Oct 2014]
Synonyms
HP4; DEF4; HP-4; HNP-4

Cat.No. Product Name Price
SHG228149 shRNA set against Human DEFA4(NM_001925.1) Inquiry
SHH276401 shRNA set against Human DEFA4 (NM_001925.1) Inquiry
SHH276405 shRNA set against Mouse DEFA4 (NM_010039.1) Inquiry
Cat.No. Product Name Price
CDFH004947 Human DEFA4 cDNA Clone(NM_001925.1) Inquiry
CDFL003540 Mouse Defa4 cDNA Clone(NM_010039.1) Inquiry
MiUTR1H-02752 DEFA4 miRNA 3'UTR clone Inquiry
MiUTR1M-03791 DEFA4 miRNA 3'UTR clone Inquiry
CDCR054664 Human DEFA4 ORF clone (NM_001925.1) Inquiry
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