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Ddx4

Official Full Name
DEAD box helicase 4
Organism
Mus musculus
GeneID
13206
Background
Enables ATP hydrolysis activity. Involved in male meiosis I; regulatory ncRNA-mediated gene silencing; and spermatogenesis. Acts upstream of with a positive effect on transposable element silencing by piRNA-mediated heterochromatin formation. Acts upstream of or within regulation of protein localization. Located in cytoplasmic ribonucleoprotein granule; nucleus; and perinuclear region of cytoplasm. Part of ribonucleoprotein complex. Is expressed in several structures, including alimentary system mesentery; aorta-gonad-mesonephros; embryo ectoderm; gonad; and gonad primordium. Orthologous to human DDX4 (DEAD-box helicase 4). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Ddx4; Mvh; VASA;

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