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DDOST

Official Full Name
dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit
Organism
Homo sapiens
GeneID
1650
Background
This gene encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. The product of this gene is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia. [provided by RefSeq, Jul 2008]
Synonyms
OST; WBP1; AGER1; CDG1R; GATD6; OST48; OKSWcl45;

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