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CTCF


Official Full Name
CCCTC-binding factor
Organism
Homo sapiens
Gene ID
10664
Background
This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
Synonyms
MRD21; FAP108; CFAP108

Cat.No. Product Name Price
SHG205737 shRNA set against Rat Ctcf(NM_031824.1) Inquiry
SHG205935 shRNA set against Mouse Ctcf(NM_181322.3) Inquiry
SHH271073 shRNA set against Human CTCF (NM_006565.3) Inquiry
SHH271077 shRNA set against Mouse CTCF (NM_181322.3) Inquiry
SHH271081 shRNA set against Rat CTCF (NM_031824.1) Inquiry
SHW005827 shRNA set against Chicken CTCF (NM_205332) Inquiry
SHW006139 shRNA set against Danio rerio CTCF (NM_001001844) Inquiry
Cat.No. Product Name Price
CDFR012954 Rat Ctcf cDNA Clone(NM_031824.1) Inquiry
MiUTR1M-03420 CTCF miRNA 3'UTR clone Inquiry
MiUTR1R-01249 CTCF miRNA 3'UTR clone Inquiry
MiUTR3H-06610 CTCF miRNA 3'UTR clone Inquiry
CDCB158512 Human CTCF ORF clone (BC014267) Inquiry
CDCB167302 Chicken CTCF ORF Clone (NM_205332) Inquiry
CDCB167614 Danio rerio CTCF ORF Clone (NM_001001844) Inquiry
CDCB187502 Rabbit CTCF ORF clone (XM_008257464.1) Inquiry
CDCR051474 Human CTCF ORF clone (NM_001191022.1) Inquiry
CDCR275492 Mouse Ctcf ORF Clone(NM_181322.3) Inquiry
CDCR379968 Rat Ctcf ORF Clone(NM_031824.1) Inquiry
CDCS409238 Human CTCF ORF Clone (BC014267) Inquiry
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