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CNTNAP2


Official Full Name
contactin associated protein 2
Organism
Homo sapiens
Gene ID
26047
Background
This gene encodes a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative PDZ binding site. This protein is localized at the juxtaparanodes of myelinated axons, and mediates interactions between neurons and glia during nervous system development and is also involved in localization of potassium channels within differentiating axons. This gene encompasses almost 1.5% of chromosome 7 and is one of the largest genes in the human genome. It is directly bound and regulated by forkhead box protein P2, a transcription factor related to speech and language development. This gene has been implicated in multiple neurodevelopmental disorders, including Gilles de la Tourette syndrome, schizophrenia, epilepsy, autism, ADHD and intellectual disability. [provided by RefSeq, Jul 2017]
Synonyms
CDFE; NRXN4; AUTS15; CASPR2; PTHSL1

Cat.No. Product Name Price
SHH266753 shRNA set against Human CNTNAP2 (NM_014141.5) Inquiry
SHH266757 shRNA set against Mouse CNTNAP2 (NM_001004357.2) Inquiry
SHG188177 shRNA set against Mouse Cntnap2(NM_001004357.2) Inquiry
SHG188259 shRNA set against Mouse Cntnap2(NM_025771.3) Inquiry
SHG188313 shRNA set against Mouse Cntnap2(NM_001004357.2) Inquiry
Cat.No. Product Name Price
CDFG016878 Mouse Cntnap2 cDNA Clone(NM_001004357.2) Inquiry
CDFL002920 Mouse Cntnap2 cDNA Clone(NM_025771.3) Inquiry
MiUTR1M-03178 CNTNAP2 miRNA 3'UTR clone Inquiry
CDCB185218 Rabbit CNTNAP2 ORF clone (XM_008258071.1) Inquiry
CDCL213544 Mouse Cntnap2 ORF Clone(NM_001004357.2) Inquiry
CDCR257594 Mouse Cntnap2 ORF Clone(NM_025771.3) Inquiry
CDCS413500 Human CNTNAP2 ORF Clone (BC113373) Inquiry
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