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CLDN12


Official Full Name
claudin 12
Organism
Homo sapiens
Gene ID
9069
Background
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is expressed in the inner ear and bladder epithelium, and it is over-expressed in colorectal carcinomas. This protein and claudin 2 are critical for vitamin D-dependent Ca2+ absorption between enterocytes. Multiple alternatively spliced transcript variants encoding the same protein have been found.[provided by RefSeq, Sep 2011]
Synonyms
RH; GUA; GURDB; II/Gu; RH II/Gu; RH-II/GU; gu-alpha; RH-II/GuA

Cat.No. Product Name Price
SHH264657 shRNA set against Human CLDN12 (NM_012129.4) Inquiry
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Cat.No. Product Name Price
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CDCR243321 Mouse Cldn12 ORF Clone(NM_001193660.1) Inquiry
CDCR243323 Mouse Cldn12 ORF Clone(NM_001193661.1) Inquiry
CDCR372390 Rat Cldn12 ORF Clone(NM_001100813.1) Inquiry
CDCS409178 Human CLDN12 ORF Clone (BC036754) Inquiry
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