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CILP


Official Full Name
cartilage intermediate layer protein
Organism
Homo sapiens
Gene ID
8483
Background
Major alterations in the composition of the cartilage extracellular matrix occur in joint disease, such as osteoarthrosis. This gene encodes the cartilage intermediate layer protein (CILP), which increases in early osteoarthrosis cartilage. The encoded protein was thought to encode a protein precursor for two different proteins; an N-terminal CILP and a C-terminal homolog of NTPPHase, however, later studies identified no nucleotide pyrophosphatase phosphodiesterase (NPP) activity. The full-length and the N-terminal domain of this protein was shown to function as an IGF-1 antagonist. An allelic variant of this gene has been associated with lumbar disc disease. [provided by RefSeq, Sep 2010]
Synonyms
CILP1; CILP-1; HsT18872

Cat.No. Product Name Price
SHH264097 shRNA set against Human CILP (NM_003613.3) Inquiry
SHG169719 shRNA set against Mouse Cilp(NM_173385.2) Inquiry
SHH264101 shRNA set against Mouse CILP (NM_173385.2) Inquiry
SHH264105 shRNA set against Rat CILP (NM_001108161.1) Inquiry
SHW013737 shRNA set against Danio rerio CILP (NM_001199362) Inquiry
Cat.No. Product Name Price
CDCB175212 Danio rerio CILP ORF Clone (NM_001199362) Inquiry
CDCR272120 Mouse Cilp ORF Clone(NM_173385.2) Inquiry
CDCS411375 Human CILP ORF Clone (BC035776) Inquiry
CDFR007809 Rat Cilp cDNA Clone(NM_001108161.1) Inquiry
MiUTR1M-03049 CILP miRNA 3'UTR clone Inquiry
MiUTR3H-06019 CILP miRNA 3'UTR clone Inquiry
CDCB180616 Rabbit CILP ORF clone (XM_008268884.1) Inquiry
CDCR374808 Rat Cilp ORF Clone(NM_001108161.1) Inquiry
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