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CEP78


Official Full Name
centrosomal protein 78
Organism
Homo sapiens
Gene ID
84131
Background
This gene encodes a centrosomal protein that is both required for the regulation of centrosome-related events during the cell cycle, and required for ciliogenesis. The encoded protein has an N-terminal leucine-rich repeat (LRR) domain with six consecutive LRR repeats, and a C-terminal coiled-coil domain. It interacts with the N-terminal catalytic domain of polo-like kinase 4 (PLK4) and colocalizes with PLK4 to the distal end of the centriole. Naturally occurring mutations in this gene cause defects in primary cilia that result in retinal degeneration and sensorineural hearing loss which are associated with cone-rod degeneration disease as well as Usher syndrome. Low expression of this gene is associated with poor prognosis of colorectal cancer patients. [provided by RefSeq, Mar 2017]
Synonyms
IP63; CRDHL; C9orf81

Cat.No. Product Name Price
SHG135493 shRNA set against Mouse Cep78(NM_198019.2) Inquiry
SHH262021 shRNA set against Human Cep78 (NM_001098802.1) Inquiry
SHH262025 shRNA set against Mouse Cep78 (NM_198019.2) Inquiry
SHH262029 shRNA set against Rat Cep78 (NM_021741.2) Inquiry
Cat.No. Product Name Price
CDCR046144 Human CEP78 ORF clone (NM_032171.1) Inquiry
CDFG005828 Human CEP78 cDNA Clone(NM_032171.1) Inquiry
CDFH003487 Human CEP78 cDNA Clone(NM_001098802.1) Inquiry
CDFR011753 Rat Cep78 cDNA Clone(NM_021741.2) Inquiry
MiUTR1M-02957 CEP78 miRNA 3'UTR clone Inquiry
MiUTR1R-02681 CEP78 miRNA 3'UTR clone Inquiry
MiUTR3H-14425 CEP78 miRNA 3'UTR clone Inquiry
MiUTR3H-14426 CEP78 miRNA 3'UTR clone Inquiry
CDCB188667 Rabbit CEP78 ORF clone (XM_002708219.2) Inquiry
CDCR046142 Human CEP78 ORF clone (NM_001098802.1) Inquiry
CDCR046146 Mouse Cep78 ORF clone (NM_198019.2) Inquiry
CDCR378800 Rat Cep78 ORF Clone(NM_021741.2) Inquiry
CDCS407457 Human CEP78 ORF Clone (BC128058) Inquiry
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