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CDH10


Official Full Name
cadherin 10
Organism
Homo sapiens
Gene ID
1008
Background
This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature cadherin protein. These integral membrane proteins mediate calcium-dependent cell-cell adhesion and are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is predominantly expressed in brain and is putatively involved in synaptic adhesions, axon outgrowth and guidance. Mutations in this gene may be associated with lung squamous cell carcinoma and colorectal cancer in human patients. [provided by RefSeq, Nov 2015]
Synonyms
CGD; CGDX; NOX2; IMD34; AMCBX2; GP91-1; GP91PHOX; p91-PHOX; GP91-PHOX

Cat.No. Product Name Price
SHG162772 shRNA set against Mouse Cdh10(NM_009865.2) Inquiry
SHH260125 shRNA set against Human CDH10 (NM_006727.3) Inquiry
SHH260129 shRNA set against Mouse CDH10 (NM_009865.2) Inquiry
SHH260133 shRNA set against Rat CDH10 (NM_001168631.1) Inquiry
SHW006087 shRNA set against Chicken CDH10 (NM_214673) Inquiry
Cat.No. Product Name Price
MiUTR1M-02839 CDH10 miRNA 3'UTR clone Inquiry
MiUTR3H-06904 CDH10 miRNA 3'UTR clone Inquiry
CDCB167562 Chicken CDH10 ORF Clone (NM_214673) Inquiry
CDCB191871 Rabbit CDH10 ORF clone (XM_002714085.2) Inquiry
CDCR005603 Human CDH10 ORF clone(NM_006727.3) Inquiry
CDCR005609 Rat CDH10 ORF clone(NM_001168631.1) Inquiry
CDCR045068 Mouse Cdh10 ORF clone (NM_009865.2) Inquiry
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