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Ccl12

Official Full Name
C-C motif chemokine ligand 12
Organism
Mus musculus
GeneID
20293
Background
Enables CCR2 chemokine receptor binding activity. Involved in angiogenesis; inflammatory response; and monocyte chemotaxis. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in central nervous system and retina. Human ortholog(s) of this gene implicated in several diseases, including Henoch-Schoenlein purpura; aggressive periodontitis; autoimmune disease (multiple); end stage renal disease; and gastrointestinal system cancer (multiple). Orthologous to human CCL2 (C-C motif chemokine ligand 2). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Ccl12; MCP-5; Scya12;

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