Pages
Products

CBFA2T2


Official Full Name
CBFA2/RUNX1 partner transcriptional co-repressor 2
Organism
Homo sapiens
Gene ID
9139
Background
In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 (AML1) gene fused to the 3'-region of the CBFA2T1 (MTG8) gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. The protein encoded by this gene binds to the AML1-MTG8 complex and may be important in promoting leukemogenesis. Several transcript variants are thought to exist for this gene, but the full-length natures of only three have been described. [provided by RefSeq, Jul 2008]
Synonyms
EHT; p85; MTGR1; ZMYND3

Cat.No. Product Name Price
SHG144339 shRNA set against Human CBFA2T2(NM_005093.3) Inquiry
SHG144329 shRNA set against Mouse Cbfa2t2(NM_172860.2) Inquiry
SHG144421 shRNA set against Human CBFA2T2(NM_001032999.2) Inquiry
SHG144465 shRNA set against Human CBFA2T2(NM_005093.3) Inquiry
SHG144469 shRNA set against Human CBFA2T2(NM_001039709.1) Inquiry
SHH255265 shRNA set against Human CBFA2T2 (NM_001032999.2) Inquiry
SHH255269 shRNA set against Mouse CBFA2T2 (NM_172860.2) Inquiry
SHH255273 shRNA set against Rat CBFA2T2 (NM_001168542.1) Inquiry
SHW000823 shRNA set against Chicken CBFA2T2 (NM_001011689) Inquiry
Cat.No. Product Name Price
CDFH002781 Human CBFA2T2 cDNA Clone(NM_001039709.1) Inquiry
MiUTR1H-01699 CBFA2T2 miRNA 3'UTR clone Inquiry
MiUTR1H-01700 CBFA2T2 miRNA 3'UTR clone Inquiry
MiUTR1H-01701 CBFA2T2 miRNA 3'UTR clone Inquiry
MiUTR1M-02557 CBFA2T2 miRNA 3'UTR clone Inquiry
CDCB162298 Chicken CBFA2T2 ORF Clone (NM_001011689) Inquiry
CDCB183594 Rabbit CBFA2T2 ORF clone (XM_008256107.1) Inquiry
CDCR041912 Human CBFA2T2 ORF clone (NM_001032999.2) Inquiry
CDCR041914 Human CBFA2T2 ORF clone (NM_001039709.1) Inquiry
CDCR041922 Mouse Cbfa2t2 ORF clone (NM_009823.1) Inquiry
CDCR271785 Mouse Cbfa2t2 ORF Clone(NM_172860.2) Inquiry
CDCS406808 Human CBFA2T2 ORF Clone (BC040344) Inquiry
CDCS406809 Human CBFA2T2 ORF Clone (BC015066) Inquiry
Quick Inquiry