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Catna1

Official Full Name
catenin alpha 1
Organism
Mus musculus
GeneID
12385
Background
Enables actin filament binding activity and identical protein binding activity. Involved in negative regulation of protein localization to nucleus. Acts upstream of or within several processes, including apical junction assembly; negative regulation of neuroblast proliferation; and regulation of signal transduction. Located in several cellular components, including intercalated disc; lamellipodium; and zonula adherens. Part of flotillin complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Used to study patterned macular dystrophy 2. Human ortholog(s) of this gene implicated in patterned macular dystrophy 2. Orthologous to human CTNNA1 (catenin alpha 1). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Ctnna1; Catna1; 2010010M04Rik;

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