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Car8

Official Full Name
carbonic anhydrase 8
Organism
Mus musculus
GeneID
12319
Background
Predicted to enable carbonate dehydratase activity and zinc ion binding activity. Acts upstream of or within positive regulation of calcium-mediated signaling. Located in cytoplasm. Is expressed in several structures, including alimentary system; brain; ear; genitourinary system; and respiratory system. Used to study cerebellar ataxia, impaired intellectual development, and dysequilibrium syndrome. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 34. Orthologous to human CA8 (carbonic anhydrase 8). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Car8; Ca8; wdl; Cals; Carp; Cals1;

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