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Car2

Official Full Name
carbonic anhydrase 2
Organism
Mus musculus
GeneID
12349
Background
Enables carbonate dehydratase activity. Involved in positive regulation of dipeptide transmembrane transport and regulation of intracellular pH. Acts upstream of or within several processes, including carbon dioxide transport; positive regulation of GABAergic synaptic transmission; and positive regulation of cellular pH reduction. Located in cytosol and myelin sheath. Is expressed in several structures, including alimentary system; brain; heart; metanephros; and sensory organ. Used to study autosomal recessive osteopetrosis 3. Human ortholog(s) of this gene implicated in autosomal recessive osteopetrosis 3 and osteopetrosis. Orthologous to human CA2 (carbonic anhydrase 2). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Car2; Ca2; CAII; Car-2; Ltw-5; Lvtw-5;

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