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PTGIS


Official Full Name
prostaglandin I2 synthase
Organism
Homo sapiens
Gene ID
5740
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis. [provided by RefSeq, Jul 2008]
Synonyms
CYP8; PGIS; PTGI; CYP8A1

Cat.No. Product Name Price
SHH386100 shRNA set against Human PTGIS (NM_000961.3) Inquiry
SHH386104 shRNA set against Mouse PTGIS (NM_008968.3) Inquiry
SHH386108 shRNA set against Rat PTGIS (NM_031557.2) Inquiry
SHR106944 shRNA set against Rat Ptgis(NM_031557.2) Inquiry
SHR106962 shRNA set against Mouse Ptgis(NM_008968.3) Inquiry
SHR107034 shRNA set against Human PTGIS(NM_000961.3) Inquiry
SHW012115 shRNA set against Danio rerio PTGIS (NM_001111160) Inquiry
Cat.No. Product Name Price
CDFH015475 Human PTGIS cDNA Clone(NM_000961.3) Inquiry
CDFR012715 Rat Ptgis cDNA Clone(NM_031557.2) Inquiry
MiUTR1H-08427 PTGIS miRNA 3'UTR clone Inquiry
MiUTR1M-09737 PTGIS miRNA 3'UTR clone Inquiry
MiUTR1R-06183 PTGIS miRNA 3'UTR clone Inquiry
CDCB173590 Danio rerio PTGIS ORF Clone (NM_001111160) Inquiry
CDCB181277 Rabbit PTGIS ORF clone (XM_008274812.1) Inquiry
CDCR246465 Mouse Ptgis ORF Clone(NM_008968.3) Inquiry
CDCR338091 Human PTGIS ORF Clone(NM_000961.3) Inquiry
CDCR379748 Rat Ptgis ORF Clone(NM_031557.2) Inquiry
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