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CYP7B1


Official Full Name
cytochrome P450 family 7 subfamily B member 1
Organism
Homo sapiens
Gene ID
9420
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis. Mutations in this gene have been associated with hereditary spastic paraplegia (SPG5 or HSP), an autosomal recessive disorder. [provided by RefSeq, Apr 2016]
Synonyms
CP7B; CBAS3; SPG5A

Cat.No. Product Name Price
SHG217953 shRNA set against Mouse Cyp7b1(NM_007825.4) Inquiry
SHH273797 shRNA set against Human Cyp7b1 (NM_004820.3) Inquiry
SHH273801 shRNA set against Mouse Cyp7b1 (NM_007825.4) Inquiry
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CDCR052900 Mouse Cyp7b1 ORF clone (NM_007825.4) Inquiry
CDCR378479 Rat Cyp7b1 ORF Clone(NM_019138.1) Inquiry
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