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cyp11c1


Official Full Name
cytochrome P450, family 11, subfamily C, polypeptide 1
Organism
Danio rerio
Gene ID
791124
Background
Predicted to enable several functions, including heme binding activity; iron ion binding activity; and steroid 11-beta-monooxygenase activity. Acts upstream of or within cortisol metabolic process; male gonad development; and mating behavior. Predicted to be located in membrane and synapse. Predicted to be active in mitochondrial inner membrane. Is expressed in Leydig cell; brain; and pleuroperitoneal region. Used to study congenital adrenal hyperplasia. Human ortholog(s) of this gene implicated in several diseases, including congenital adrenal hyperplasia; corticosterone methyloxidase deficiency 1; diabetes mellitus (multiple); hypertension (multiple); and primary hyperaldosteronism (multiple). Orthologous to human CYP11B1 (cytochrome P450 family 11 subfamily B member 1) and CYP11B2 (cytochrome P450 family 11 subfamily B member 2). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
cyp11b2

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