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cxcr4b


Official Full Name
chemokine (C-X-C motif), receptor 4b
Organism
Danio rerio
Gene ID
114447
Background
Enables G protein-coupled chemoattractant receptor activity. Involved in Kupffer's vesicle development and localization of cell. Acts upstream of or within several processes, including nervous system development; posterior lateral line neuromast primordium migration; and regulation of chemotaxis. Located in plasma membrane. Is expressed in several structures, including anterior neural keel; immature eye; mesoderm; nervous system; and neurogenic placode. Human ortholog(s) of this gene implicated in several diseases, including WHIM syndrome 1; bone disease (multiple); hematologic cancer (multiple); pancreatic adenocarcinoma; and prostate cancer. Orthologous to human CXCR4 (C-X-C motif chemokine receptor 4). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
CXCR4; cb403; zgc:109863

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