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CXCL1

Official Full Name
C-X-C motif chemokine ligand 1
Organism
Homo sapiens
GeneID
2919
Background
This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4. [provided by RefSeq, Sep 2014]
Synonyms
FSP; GRO1; GROa; MGSA; NAP-3; SCYB1; MGSA-a;

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