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CSK


Official Full Name
C-terminal Src kinase
Organism
Homo sapiens
Gene ID
1445
Background
The protein encoded by this gene is involved in multiple pathways, including the regulation of Src family kinases. It plays an important role in T-cell activation through its association with the protein encoded by the protein tyrosine phosphatase, non-receptor type 22 (PTPN22) gene. This protein also phosphorylates C-terminal tyrosine residues on multiple substrates, including the protein encoded by the SRC proto-oncogene, non-receptor tyrosine kinase gene. Phosphorylation suppresses the kinase activity of the Src family tyrosine kinases. An intronic polymorphism (rs34933034) in this gene has been found to affect B-cell activation and is associated with systemic lupus erythematosus (SLE). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2017]
Synonyms
VHX; JKAP; JSP1; MKPX; JSP-1; MKP-x; LMWDSP2; LMW-DSP2

Cat.No. Product Name Price
LV09860L human CSK (NM_004383) lentivirus particles Inquiry
Cat.No. Product Name Price
SHG202969 shRNA set against Rat Csk(NM_001030039.1) Inquiry
SHG202987 shRNA set against Mouse Csk(NM_007783.2) Inquiry
SHH270337 shRNA set against Human CSK (NM_004383.2) Inquiry
SHH270341 shRNA set against Mouse CSK (NM_007783.2) Inquiry
SHH270345 shRNA set against Rat CSK (NM_001030039.1) Inquiry
SHW005919 shRNA set against Chicken CSK (NM_205425) Inquiry
SHW010680 shRNA set against Danio rerio CSK (NM_001077599) Inquiry
Cat.No. Product Name Price
CDFH004342 Human CSK cDNA Clone(NM_001127190.1) Inquiry
CDFR004162 Rat Csk cDNA Clone(NM_001030039.1) Inquiry
MiUTR1H-02468 CSK miRNA 3'UTR clone Inquiry
MiUTR1H-02469 CSK miRNA 3'UTR clone Inquiry
MiUTR1M-03381 CSK miRNA 3'UTR clone Inquiry
MiUTR1R-01219 CSK miRNA 3'UTR clone Inquiry
SKO0409 CSK Validated sgRNA vector Inquiry
CDCB167394 Chicken CSK ORF Clone (NM_205425) Inquiry
CDCB172155 Danio rerio CSK ORF Clone (NM_001077599) Inquiry
CDCB182031 Rabbit CSK ORF clone (XM_008252410.1) Inquiry
CDCH384240 Human CSK ORF clone(NM_004383.2) Inquiry
CDCL183742 Human CSK ORF clone(NM_001127190.1) Inquiry
CDCL183743 Mouse CSK ORF clone(NM_007783.2) Inquiry
CDCR371191 Rat Csk ORF Clone(NM_001030039.1) Inquiry
Cat.No. Product Name Price
CC-358 CSK Easy KO Kit Inquiry
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