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csf1ra


Official Full Name
colony stimulating factor 1 receptor, a
Organism
Danio rerio
Gene ID
64274
Background
Predicted to enable growth factor binding activity and macrophage colony-stimulating factor receptor activity. Acts upstream of or within several processes, including immune response in brain or nervous system; macrophage chemotaxis; and myeloid cell development. Predicted to be located in membrane. Predicted to be part of CSF1-CSF1R complex and receptor complex. Predicted to be active in plasma membrane. Is expressed in several structures, including hematopoietic cell; hematopoietic system; integument; nervous system; and neural crest cell. Used to study CSF1R-related brain malformation and osteopetrosis. Human ortholog(s) of this gene implicated in adult-onset leukoencephalopathy with axonal spheroids and pigmented glia; diabetes mellitus; gastrointestinal system cancer (multiple); lung cancer (multiple); and renal cell carcinoma. Orthologous to human CSF1R (colony stimulating factor 1 receptor). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
fms; csf1r; CSF-1R; M-CSF-R; panther

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