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CRLF1

Official Full Name
cytokine receptor-like factor 1
Background
This gene encodes a member of the cytokine type I receptor family. The protein forms a secreted complex with cardiotrophin-like cytokine factor 1 and acts on cells expressing ciliary neurotrophic factor receptors. The complex can promote survival of neuronal cells. Mutations in this gene result in Crisponi syndrome and cold-induced sweating syndrome.
Synonyms
CRLF1; cytokine receptor-like factor 1; CISS; CISS1; CLF; CLF 1; cold induced sweating syndrome; CISS 1; CLF1; CRLF 1; Cytokine like factor 1; Cytokine receptor like factor 1; NR 6; NR6; ZcytoR 5; ZcytoR5; cytokine-like factor 1; class I cytokine receptor; cytokine type 1 receptor CRLP-1; CLF-1

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