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CREBL2


Official Full Name
cAMP responsive element binding protein like 2
Organism
Homo sapiens
Gene ID
1389
Background
cAMP response element (CRE)-binding protein-like-2 (CREBL2) was identified in a search to find genes in a commonly deleted region on chromosome 12p13 flanked by ETV6 and CDKN1B genes, frequently associated with hematopoietic malignancies, as well as breast, non-small-cell lung and ovarian cancers. CREBL2 shares a 41% identity with CRE-binding protein (CREB) over a 48-base long region which encodes the bZip domain of CREB. The bZip domain consists of about 30 amino acids rich in basic residues involved in DNA binding, followed by a leucine zipper motif involved in protein dimerization. This suggests that CREBL2 encodes a protein with DNA binding capabilities. The occurance of CREBL2 deletion in malignancy suggests that CREBL2 may act as a tumor suppressor gene. [provided by RefSeq, Jul 2008]
Synonyms
IRS5; IRS-5

Cat.No. Product Name Price
SHG198379 shRNA set against Mouse Crebl2(NM_177687.3) Inquiry
SHH269385 shRNA set against Mouse CREBL2 (NM_177687.3) Inquiry
SHG198343 shRNA set against Rat Crebl2(NM_001015027.1) Inquiry
SHG198397 shRNA set against Human CREBL2(NM_001310.2) Inquiry
SHH269381 shRNA set against Human CREBL2 (NM_001310.2) Inquiry
SHH269389 shRNA set against Rat CREBL2 (NM_001015027.1) Inquiry
SHW004316 shRNA set against Chicken CREBL2 (NM_001278110) Inquiry
SHW006691 shRNA set against Danio rerio CREBL2 (NM_001002702) Inquiry
Cat.No. Product Name Price
CDFH004235 Human CREBL2 cDNA Clone(NM_001310.2) Inquiry
CDFR003425 Rat Crebl2 cDNA Clone(NM_001015027.1) Inquiry
MiUTR1H-02418 CREBL2 miRNA 3'UTR clone Inquiry
MiUTR1R-01172 CREBL2 miRNA 3'UTR clone Inquiry
CDCB165791 Chicken CREBL2 ORF Clone (NM_001278110) Inquiry
CDCB168166 Danio rerio CREBL2 ORF Clone (NM_001002702) Inquiry
CDCB187442 Rabbit CREBL2 ORF clone (XM_002712651.2) Inquiry
CDCR274147 Mouse Crebl2 ORF Clone(NM_177687.3) Inquiry
CDCR280500 Human CREBL2 ORF Clone(NM_001310.2) Inquiry
CDCR370414 Rat Crebl2 ORF Clone(NM_001015027.1) Inquiry
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