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CPOX

Official Full Name
coproporphyrinogen oxidase
Organism
Homo sapiens
GeneID
1371
Background
The protein encoded by this gene is the sixth enzyme of the heme biosynthetic pathway. The encoded enzyme is soluble and found in the intermembrane space of mitochondria. This enzyme catalyzes the stepwise oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX, a precursor of heme. Defects in this gene are a cause of hereditary coproporphyria (HCP).[provided by RefSeq, Oct 2009]
Synonyms
COX; CPO; CPX; HCP; HARPO;

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