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COX6A1


Official Full Name
cytochrome c oxidase subunit 6A1
Organism
Homo sapiens
Gene ID
1337
Background
Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in the electron transfer and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 1 (liver isoform) of subunit VIa, and polypeptide 1 is found in all non-muscle tissues. Polypeptide 2 (heart/muscle isoform) of subunit VIa is encoded by a different gene, and is present only in striated muscles. These two polypeptides share 66% amino acid sequence identity. It has been reported that there may be several pseudogenes on chromosomes 1, 6, 7q21, 7q31-32 and 12. However, only one pseudogene (COX6A1P) on chromosome 1p31.1 has been documented. [provided by RefSeq, Jul 2008]
Synonyms
COX6A; CMTRID; COX6AL

Cat.No. Product Name Price
SHH268313 shRNA set against Mouse COX6A1 (NM_007748.3) Inquiry
SHW007319 shRNA set against Danio rerio COX6A1 (NM_001005592) Inquiry
SHW003844 shRNA set against Chicken COX6A1 (NM_001277509) Inquiry
SHW003845 shRNA set against Chicken COX6A1 (NM_001277510) Inquiry
Cat.No. Product Name Price
MiUTR1M-03264 COX6A1 miRNA 3'UTR clone Inquiry
MiUTR3H-04644 COX6A1 miRNA 3'UTR clone Inquiry
SKO0403 COX6A1 Validated sgRNA vector Inquiry
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CDCB165320 Chicken COX6A1 ORF Clone (NM_001277510) Inquiry
CDCB168794 Danio rerio COX6A1 ORF Clone (NM_001005592) Inquiry
CDCB195205 Rabbit COX6A1 ORF clone (NM_001170883.2) Inquiry
CDCR049900 Mouse Cox6a1 ORF clone (NM_007748.3) Inquiry
CDCS411753 Human COX6A1 ORF Clone (BC007723) Inquiry
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