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CORIN

Official Full Name
corin, serine peptidase
Organism
Homo sapiens
GeneID
10699
Background
This gene encodes a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. The encoded protein converts pro-atrial natriuretic peptide to biologically active atrial natriuretic peptide, a cardiac hormone that regulates blood volume and pressure. This protein may also function as a pro-brain-type natriuretic peptide convertase. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2013]
Synonyms
CRN; ATC2; Lrp4; PEE5; CMH30; TMPRSS10;

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