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COG5

Official Full Name
component of oligomeric golgi complex 5
Organism
Homo sapiens
GeneID
10466
Background
The protein encoded by this gene is one of eight proteins (Cog1-8) which form a Golgi-localized complex (COG) required for normal Golgi morphology and function. The encoded protein is organized with conserved oligomeric Golgi complex components 6, 7 and 8 into a sub-complex referred to as lobe B. Alternative splicing results in multiple transcript variants. Mutations in this gene result in congenital disorder of glycosylation type 2I.[provided by RefSeq, Jan 2011]
Synonyms
CDG2I; GTC90; GOLTC1;

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