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COASY


Official Full Name
Coenzyme A synthase
Organism
Homo sapiens
Gene ID
80347
Background
Coenzyme A (CoA) functions as a carrier of acetyl and acyl groups in cells and thus plays an important role in numerous synthetic and degradative metabolic pathways in all organisms. In eukaryotes, CoA and its derivatives are also involved in membrane trafficking and signal transduction. This gene encodes the bifunctional protein coenzyme A synthase (CoAsy) which carries out the last two steps in the biosynthesis of CoA from pantothenic acid (vitamin B5). The phosphopantetheine adenylyltransferase domain of this bifunctional protein catalyzes the conversion of 4'-phosphopantetheine into dephospho-coenzyme A (dpCoA) while its dephospho-CoA kinase domain completes the final step by phosphorylating dpCoA to form CoA. Mutations in this gene are associated with neurodegeneration with brain iron accumulation (NBIA). Alternative splicing results in multiple isoforms. [provided by RefSeq, Apr 2014]
Synonyms
NBP; DPCK; PPAT; UKR1; NBIA6; PCH12; pOV-2

Cat.No. Product Name Price
SHG188605 shRNA set against Mouse Coasy(NM_027896.4) Inquiry
SHG188623 shRNA set against Rat Coasy(NM_001006954.1) Inquiry
SHH266841 shRNA set against Mouse COASY (NM_027896.4) Inquiry
SHH266845 shRNA set against Rat COASY (NM_001006954.1) Inquiry
SHW007185 shRNA set against Danio rerio COASY (NM_001004577) Inquiry
Cat.No. Product Name Price
CDCS407114 Human COASY ORF Clone (BC020985) Inquiry
MiUTR3H-10845 COASY miRNA 3'UTR clone Inquiry
MiUTR1R-01101 COASY miRNA 3'UTR clone Inquiry
MiUTR1M-03183 COASY miRNA 3'UTR clone Inquiry
CDFR001532 Rat Coasy cDNA Clone(NM_001006954.1) Inquiry
CDFL002924 Mouse Coasy cDNA Clone(NM_027896.4) Inquiry
MiUTR3H-10846 COASY miRNA 3'UTR clone Inquiry
MiUTR3H-10847 COASY miRNA 3'UTR clone Inquiry
CDCR368593 Rat Coasy ORF Clone(NM_001006954.1) Inquiry
CDCS407115 Human COASY ORF Clone (BC067254) Inquiry
CDCR344577 Human COASY ORF Clone(NM_001042532.3) Inquiry
CDCR260675 Mouse Coasy ORF Clone(NM_027896.4) Inquiry
CDCB190947 Rabbit COASY ORF clone (XM_008271510.1) Inquiry
CDCB168660 Danio rerio COASY ORF Clone (NM_001004577) Inquiry
CDCB158200 Human COASY ORF clone (BC067254) Inquiry
CDCS407113 Human COASY ORF Clone (BC006354) Inquiry
CDCB156149 Cynomolgus COASY ORF clone (XM_005584256.1) Inquiry
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