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CNOT1

Official Full Name
CCR4-NOT transcription complex subunit 1
Organism
Homo sapiens
GeneID
23019
Background
Enables armadillo repeat domain binding activity; molecular adaptor activity; and nuclear receptor binding activity. Contributes to poly(A)-specific ribonuclease activity. Involved in several processes, including negative regulation of intracellular signal transduction; positive regulation of cytoplasmic mRNA processing body assembly; and regulation of gene expression. Located in P-body and cytosol. Part of CCR4-NOT complex. Implicated in Vissers-Bodmer syndrome and holoprosencephaly 12. [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
NOT1; CDC39; HPE12; NOT1H; VIBOS; AD-005;

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