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CLDN11


Official Full Name
claudin 11
Organism
Homo sapiens
Gene ID
5010
Background
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is a major component of central nervous system (CNS) myelin and plays an important role in regulating proliferation and migration of oligodendrocytes. Mouse studies showed that the gene deficiency results in deafness and loss of the Sertoli cell epithelial phenotype in the testis. This protein is a tight junction protein at the human blood-testis barrier (BTB), and the BTB disruption is related to a dysfunction of this gene. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Aug 2010]
Synonyms
OSP; OTM; HLD22

Cat.No. Product Name Price
SHG180087 shRNA set against Rat Cldn11(NM_053457.2) Inquiry
SHG180287 shRNA set against Human CLDN11(NM_005602.5) Inquiry
SHH252433 shRNA set against Human C7orf33 (NM_145304.2) Inquiry
SHH264645 shRNA set against Human CLDN11 (NM_005602.5) Inquiry
SHH264649 shRNA set against Mouse CLDN11 (NM_008770.3) Inquiry
SHH264653 shRNA set against Rat CLDN11 (NM_053457.2) Inquiry
SHW015172 shRNA set against Danio rerio CLDN11B (NM_131772) Inquiry
Cat.No. Product Name Price
CDFG009003 Human C7orf33 cDNA Clone(NM_145304.2) Inquiry
CDFR013190 Rat Cldn11 cDNA Clone(NM_053457.2) Inquiry
MiUTR1H-01489 C7ORF33 miRNA 3'UTR clone Inquiry
MiUTR1H-02189 CLDN11 miRNA 3'UTR clone Inquiry
MiUTR1R-01026 CLDN11 miRNA 3'UTR clone Inquiry
CDCB176647 Danio rerio CLDN11B ORF Clone (NM_131772) Inquiry
CDCB186512 Rabbit CLDN11 ORF clone (XM_002716414.2) Inquiry
CDCR047680 Human CLDN11 ORF clone (NM_001185056.1) Inquiry
CDCR246094 Mouse Cldn11 ORF Clone(NM_008770.3) Inquiry
CDCR318440 Human C7orf33 ORF Clone(NM_145304.2) Inquiry
CDCR380277 Rat Cldn11 ORF Clone(NM_053457.2) Inquiry
CDCS412340 Human CLDN11 ORF Clone (BC013577) Inquiry
CDCS418226 Human C7ORF33 ORF Clone (BC021251) Inquiry
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