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CKAP5


Official Full Name
cytoskeleton associated protein 5
Organism
Homo sapiens
Gene ID
9793
Background
This gene encodes a cytoskeleton-associated protein which belongs to the TOG/XMAP215 family. The N-terminal half of this protein contains a microtubule-binding domain and the C-terminal half contains a KXGS motif for binding tubulin dimers. This protein has two distinct roles in spindle formation; it protects kinetochore microtubules from depolymerization and plays an essential role in centrosomal microtubule assembly. This protein may be necessary for the proper interaction of microtubules with the cell cortex for directional cell movement. It also plays a role in translation of the myelin basic protein (MBP) mRNA by interacting with heterogeneous nuclear ribonucleoprotein (hnRNP) A2, which associates with MBP. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
Synonyms
TOG; MSPS; TOGp; CHTOG; ch-TOG

Cat.No. Product Name Price
SHH264348 shRNA set against Mouse CKAP5 (NM_029437.2) Inquiry
SHH264341 shRNA set against Human CKAP5 (NM_014756.3) Inquiry
SHW003382 shRNA set against Chicken CKAP5 (NM_001199646) Inquiry
SHW009451 shRNA set against Danio rerio CKAP5 (NM_001037667) Inquiry
Cat.No. Product Name Price
MiUTR3H-11670 CKAP5 miRNA 3'UTR clone Inquiry
MiUTR3H-11671 CKAP5 miRNA 3'UTR clone Inquiry
CDCB164857 Chicken CKAP5 ORF Clone (NM_001199646) Inquiry
CDCB170926 Danio rerio CKAP5 ORF Clone (NM_001037667) Inquiry
CDCB187200 Rabbit CKAP5 ORF clone (XM_008270443.1) Inquiry
CDCR240461 Mouse Ckap5 ORF Clone(NM_001165989.1) Inquiry
CDCR262644 Mouse Ckap5 ORF Clone(NM_029437.2) Inquiry
CDCR298193 Human CKAP5 ORF Clone(NM_014756.3) Inquiry
CDCS406401 Human CKAP5 ORF Clone (BC035554) Inquiry
CDCS406402 Human CKAP5 ORF Clone (BC120869) Inquiry
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