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chmp2bb


Official Full Name
charged multivesicular body protein 2Bb
Organism
Danio rerio
Gene ID
405840
Background
Predicted to be involved in endosome transport via multivesicular body sorting pathway; late endosome to vacuole transport; and protein transport. Predicted to act upstream of or within vacuolar transport. Predicted to be located in cytosol and late endosome membrane. Predicted to be part of ESCRT III complex. Predicted to be active in multivesicular body. Is expressed in gut; nervous system; and trunk. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis; frontotemporal dementia; and frontotemporal dementia and/or amyotrophic lateral sclerosis 7. Orthologous to human CHMP2B (charged multivesicular body protein 2B). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
chmp2b; chmp2bl; zgc:77025

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