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CHD4

Official Full Name
chromodomain helicase DNA binding protein 4
Organism
Homo sapiens
GeneID
1108
Background
The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]
Synonyms
CHD-4; Mi-2b; SIHIWES; Mi2-BETA;

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