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CHD3


Official Full Name
chromodomain helicase DNA binding protein 3
Organism
Homo sapiens
Gene ID
1107
Background
This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Synonyms
ZFH; Mi-2a; SNIBCPS; Mi2-ALPHA

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CDCR007401 Human CHD3 ORF clone(NM_001005273.2) Inquiry
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