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Official Full Name
choline O-acetyltransferase
Organism
Mus musculus
GeneID
12647
Background
Enables choline O-acetyltransferase activity. Acts upstream of or within several processes, including adult walking behavior; establishment of synaptic specificity at neuromuscular junction; and rhythmic excitation. Located in axon; cytoplasm; and neuronal cell body. Is expressed in several structures, including alimentary system; cranium; heart; nervous system; and retina. Used to study congenital myasthenic syndrome 6. Human ortholog(s) of this gene implicated in Alzheimer's disease and congenital myasthenic syndrome 6. Orthologous to human CHAT (choline O-acetyltransferase). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Chat; CHOACTase; B230380D24Rik;

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