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CDKN2B


Official Full Name
cyclin dependent kinase inhibitor 2B
Organism
Homo sapiens
Gene ID
1030
Background
This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta, which suggested its role in the TGF beta induced growth inhibition. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008]
Synonyms
P15; MTS2; TP15; CDK4I; INK4B; p15INK4b

Cat.No. Product Name Price
AD03494Z Human CDKN2B adenoviral particles Inquiry
Cat.No. Product Name Price
SHG164413 shRNA set against Human CDKN2B(NM_004936.3) Inquiry
SHG164395 shRNA set against Rat Cdkn2b(NM_130812.2) Inquiry
SHG165527 shRNA set against Human CDKN2B(NM_078487.2) Inquiry
SHH260881 shRNA set against Human CDKN2B (NM_004936.3) Inquiry
SHH260885 shRNA set against Mouse CDKN2B (NM_007670.4) Inquiry
SHH260889 shRNA set against Rat CDKN2B (NM_130812.2) Inquiry
SHW004946 shRNA set against Chicken CDKN2B (NM_204433) Inquiry
Cat.No. Product Name Price
CDFG007302 Human CDKN2B cDNA Clone(NM_078487.2) Inquiry
CDFH003352 Human CDKN2B cDNA Clone(NM_004936.3) Inquiry
CDFR013929 Rat Cdkn2b cDNA Clone(NM_130812.2) Inquiry
MiUTR1H-02000 CDKN2B miRNA 3'UTR clone Inquiry
MiUTR1H-02001 CDKN2B miRNA 3'UTR clone Inquiry
MiUTR1R-00918 CDKN2B miRNA 3'UTR clone Inquiry
SKO0102 CDKN2B Validated sgRNA vector Inquiry
CDCB166421 Chicken CDKN2B ORF Clone (NM_204433) Inquiry
CDCB186746 Rabbit CDKN2B ORF clone (XM_002708053.2) Inquiry
CDCR006062 Mouse CDKN2B ORF clone(NM_007670.4) Inquiry
CDCR045532 Human CDKN2B ORF clone (NM_078487.2) Inquiry
CDCR289178 Human CDKN2B ORF Clone(NM_004936.3) Inquiry
CDCR380963 Rat Cdkn2b ORF Clone(NM_130812.2) Inquiry
CDCS412027 Human CDKN2B ORF Clone (BC014469) Inquiry
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