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CDK2AP1


Official Full Name
cyclin dependent kinase 2 associated protein 1
Organism
Homo sapiens
Gene ID
8099
Background
The protein encoded by this gene is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S-phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation. This gene thus plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012]
Synonyms
DOC1; ST19; DORC1; doc-1; p12DOC-1

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SHG164065 shRNA set against Mouse Cdk2ap1(NM_013812.2) Inquiry
SHH260581 shRNA set against Human CDK2AP1 (NM_004642.3) Inquiry
SHH260585 shRNA set against Mouse CDK2AP1 (NM_013812.2) Inquiry
SHH260589 shRNA set against Rat CDK2AP1 (NM_001113751.1) Inquiry
SHW002271 shRNA set against Chicken CDK2AP1 (NM_001039264) Inquiry
Cat.No. Product Name Price
CDFR009327 Rat Cdk2ap1 cDNA Clone(NM_001113751.1) Inquiry
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CDCB163746 Chicken CDK2AP1 ORF Clone (NM_001039264) Inquiry
CDCB189239 Rabbit CDK2AP1 ORF clone (XM_008251627.1) Inquiry
CDCR045366 Mouse Cdk2ap1 ORF clone (NM_013812.2) Inquiry
CDCR376374 Rat Cdk2ap1 ORF Clone(NM_001113751.1) Inquiry
CDCS411889 Human CDK2AP1 ORF Clone (BC034717) Inquiry
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