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CDH12


Official Full Name
cadherin 12
Organism
Homo sapiens
Gene ID
1010
Background
This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature cadherin protein. These integral membrane proteins mediate calcium-dependent cell-cell adhesion and are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis. [provided by RefSeq, Nov 2015]
Synonyms
CDHB

Cat.No. Product Name Price
SHH260149 shRNA set against Human Cdh12 (NM_004061.3) Inquiry
SHH260153 shRNA set against Mouse Cdh12 (NM_001008420.2) Inquiry
Cat.No. Product Name Price
CDCL183011 Human Cadherin-12 ORF clone(NM_004061.3) Inquiry
MiUTR1M-02841 CDH12 miRNA 3'UTR clone Inquiry
MiUTR3H-03478 CDH12 miRNA 3'UTR clone Inquiry
CDCB156732 Cynomolgus CDH12 ORF clone Inquiry
CDCB156860 Rat CDH12 ORF clone (XM_229369.5) Inquiry
CDCB193334 Rabbit CDH12 ORF clone (XM_002714080.2) Inquiry
CDCL213001 Mouse Cdh12 ORF Clone(NM_001008420.2) Inquiry
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