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CD209


Official Full Name
CD209 molecule
Organism
Homo sapiens
Gene ID
30835
Background
This gene encodes a C-type lectin that functions in cell adhesion and pathogen recognition. This receptor recognizes a wide range of evolutionarily divergent pathogens with a large impact on public health, including leprosy and tuberculosis mycobacteria, the Ebola, hepatitis C, HIV-1 and Dengue viruses, and the SARS-CoV acute respiratory syndrome coronavirus. The protein is organized into four distinct domains: a C-terminal carbohydrate recognition domain, a flexible tandem-repeat neck domain, a transmembrane region and an N-terminal cytoplasmic domain involved in internalization. This gene is closely related in terms of both sequence and function to a neighboring gene, CLEC4M (Gene ID: 10332), also known as L-SIGN. The two genes differ in viral recognition and expression patterns, with this gene showing high expression on the surface of dendritic cells. Polymorphisms in the neck region are associated with protection from HIV-1 infection, while single nucleotide polymorphisms in the promoter of this gene are associated with differing resistance and susceptibility to and severity of infectious disease, including rs4804803, which is associated with SARS severity. [provided by RefSeq, May 2020]
Synonyms
CDSIGN; CLEC4L; DC-SIGN; DC-SIGN1; hDC-SIGN

Cat.No. Product Name Price
SHH258681 shRNA set against Human CD209 (NM_021155.3) Inquiry
SHW013744 shRNA set against Danio rerio CD209 (NM_001199373) Inquiry
Cat.No. Product Name Price
CDFH003067 Human CD209 cDNA Clone(NM_001144893.1) Inquiry
CDFH003068 Human CD209 cDNA Clone(NM_001144894.1) Inquiry
CDFH003069 Human CD209 cDNA Clone(NM_001144895.1) Inquiry
CDFH003070 Human CD209 cDNA Clone(NM_001144896.1) Inquiry
CDFH003071 Human CD209 cDNA Clone(NM_001144897.1) Inquiry
CDFH003072 Human CD209 cDNA Clone(NM_001144899.1) Inquiry
MiUTR4H-TG01873 CD209 miRNA 3'UTR clone Inquiry
CDCB175219 Danio rerio CD209 ORF Clone (NM_001199373) Inquiry
CDCR044028 Human CD209 ORF clone (NM_001144899.1) Inquiry
CDCR044030 Human CD209 ORF clone (NM_001144897.1) Inquiry
CDCR044032 Human CD209 ORF clone (NM_001144896.1) Inquiry
CDCR044034 Human CD209 ORF clone (NM_001144895.1) Inquiry
CDCR044036 Human CD209 ORF clone (NM_001144894.1) Inquiry
CDCR044038 Human CD209 ORF clone (NM_001144893.1) Inquiry
CDCS408420 Human CD209 ORF Clone (BC110615) Inquiry
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