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CCRL1

Official Full Name
C-X3-C motif chemokine receptor 1
Organism
Homo sapiens
GeneID
1524
Background
Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
Synonyms
CX3CR1; V28; CCRL1; GPR13; CMKDR1; GPRV28; CMKBRL1;

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