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CCDC88C


Official Full Name
coiled-coil domain containing 88C
Organism
Homo sapiens
Gene ID
440193
Background
This gene encodes a ubiquitously expressed coiled-coil domain-containing protein that interacts with the dishevelled protein and is a negative regulator of the Wnt signalling pathway. The protein encoded by this gene has a PDZ-domain binding motif in its C-terminus with which it interacts with the dishevelled protein. Dishevelled is a scaffold protein involved in the regulation of the Wnt signaling pathway. The Wnt signaling pathway plays an important role in embryonic development, tissue maintenance, and cancer progression. Mutations in this gene cause autosomal recessive, primary non-syndromic congenital hydrocephalus; a condition characterized by excessive accumulation of cerebrospinal fluid in the ventricles of the brain. [provided by RefSeq, Jan 2013]
Synonyms
HYC1; DAPLE; HKRP2; SCA40; KIAA1509

Cat.No. Product Name Price
SHH257273 shRNA set against Human CCDC88C (NM_001080414.3) Inquiry
SHH257277 shRNA set against Mouse CCDC88C (NM_026681.4) Inquiry
Cat.No. Product Name Price
CDFL002331 Mouse Ccdc88c cDNA Clone(NM_026681.4) Inquiry
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CDCB187959 Rabbit CCDC88C ORF clone (XM_008271917.1) Inquiry
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CDCS407294 Human CCDC88C ORF Clone (BC035914) Inquiry
CDCS407295 Human CCDC88C ORF Clone (BC032316) Inquiry
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