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caspa


Official Full Name
caspase a
Organism
Danio rerio
Gene ID
57933
Background
Enables Pyrin domain binding activity and cysteine-type endopeptidase activity. Involved in self proteolysis. Acts upstream of or within several processes, including embryonic viscerocranium morphogenesis; innate immune response; and pyroptotic inflammatory response. Part of NLRP1 inflammasome complex. Is expressed in several structures, including digestive system; heart; hematopoietic system; integument; and male organism. Orthologous to several human genes including CASP4 (caspase 4). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
casp1; caspy; fa93b02; wu:fa93b02; zgc:109869

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