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Casp12

Official Full Name
caspase 12
Organism
Mus musculus
GeneID
12364
Background
Enables cysteine-type endopeptidase activity. Involved in intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress and self proteolysis. Acts upstream of or within endoplasmic reticulum unfolded protein response and fibroblast apoptotic process. Located in endoplasmic reticulum. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and immune system. Orthologous to human CASP12 (caspase 12 (gene/pseudogene)). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Casp12;

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