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CAND1


Official Full Name
cullin associated and neddylation dissociated 1
Organism
Homo sapiens
Gene ID
55832
Background
This gene encodes an essential regulator of Cullin-RING ubiquitin ligases, which are in involved in ubiquitinylation of proteins degraded by the Ub proteasome system. The encoded protein binds to unneddylated cullin-RING box protein complexes and acts as an inhibitor of cullin neddylation and of Skp1, cullin, and F box ubiquitin ligase complex assembly and activity. In mammalian cell culture, this protein predominantly localizes to the cytoplasm. Knockdown of this gene in preadipocytes results in blocked adipogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016]
Synonyms
TIP120; TIP120A

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SHH254185 shRNA set against Human CAND1 (NM_018448.3) Inquiry
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SHH254193 shRNA set against Rat CAND1 (NM_054004.2) Inquiry
SHW018536 shRNA set against Danio rerio CAND1 (NM_213485) Inquiry
Cat.No. Product Name Price
CDFL002145 Mouse Cand1 cDNA Clone(NM_027994.1) Inquiry
MiUTR4H-TG01598 CAND1 miRNA 3'UTR clone Inquiry
CDCB180011 Danio rerio CAND1 ORF Clone (NM_213485) Inquiry
CDCB189031 Rabbit CAND1 ORF clone (XM_008256760.1) Inquiry
CDCL183036 Human CAND1 ORF clone(NM_018448.3) Inquiry
CDCR041144 Mouse Cand1 ORF clone (NM_027994.1) Inquiry
CDCR380739 Rat Cand1 ORF Clone(NM_054004.2) Inquiry
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