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C5ORF20

Official Full Name
dendritic cell associated nuclear protein 1
Organism
Homo sapiens
GeneID
140947
Background
This intronless gene is specifically expressed in dendritic cells (DCs), which are potent antigen-presenting cells involved in activating naive T cells to initiate antigen-specific immune response. The encoded protein is localized mainly in the perinucleus. One of the alleles (A/T) of this gene, that causes premature translation termination at aa 117, has been associated with an increased prevalence of major depression in humans. [provided by RefSeq, Jul 2008]
Synonyms
DCNP1; C5orf20;

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