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C21orf33

Official Full Name
chromosome 21 open reading frame 33
Background
This gene encodes a potential mitochondrial protein that is a member of the DJ-1/PfpI gene family. This protein is overexpressed in fetal Down syndrome brain. Alternate splicing results in multiple transcript variants.
Synonyms
C21ORF33; chromosome 21 open reading frame 33; ES1 protein homolog, mitochondrial; D21S2048E; ES1; GT335; HES1; KNP I; KNP Ia; KNPH; KNPI; Keio novel protein I; human HES1 protein, homolog to E.coli and zebrafish ES1 protein

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