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C1ORF56


Official Full Name
chromosome 1 open reading frame 56
Organism
Homo sapiens
Gene ID
54964
Background
This gene is a proto-oncogene whose promoter is methylated by DNA methyltransferase 3B (DNMT3B), which represses the proto-oncogene. However, a catalytically inactive isoform of DNMT3B is overexpressed in lymphomas, leading to hypomethylation of the proto-oncogene's promoter and derepression of the proto-oncogene. [provided by RefSeq, Sep 2016]
Synonyms
MENT

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