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C13ORF18

Official Full Name
rubicon like autophagy enhancer
Organism
Homo sapiens
GeneID
80183
Background
This gene encodes a cysteine-rich protein that contains a putative zinc-RING and/or ribbon domain. The encoded protein is related to Run domain Beclin-1-interacting and cysteine-rich domain-containing protein, which plays a role in endocytic trafficking and autophagy. In cervical cancer cell lines, this gene is expressed at low levels and may function as a tumor suppressor. Promoter hypermethylation of this gene is observed in cervical cancer cell lines and tissue derived from human patients. [provided by RefSeq, Mar 2017]
Synonyms
RUBCNL; PACER; C13orf18; KIAA0226L;

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